Gene Information
Gene NameJSP1
OrganismHomo sapiens (Human)
Gene Length184
Protein NamesDual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9NRW4
Gene CardDUSP22
Uniprot IDQ9NRW4
PfamPF00782
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:11717427}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1WRM  (X-ray  1.50A  4WOH  (X-ray  1.34A  6L1S  (X-ray  1.36A  6LMY  (X-ray  1.50A  6LOT  (X-ray  1.69A  6LOU  (X-ray  1.53A  6LVQ  (X-ray  1.38A  7C8S  (X-ray  1.31A 
DBSNP rs7768224 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:20553486}.
Mouse PG classificationNA
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