| Gene Information | |
|---|---|
| Gene Name | SLC19A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 497 |
| Protein Names | Thiamine transporter 1 (ThTr-1) (ThTr1) (Solute carrier family 19 member 2) (Thiamine carrier 1) (TC1) |
| Target Name | solute carrier family 19 member 2 |
| Target Type | Literature-reported target |
| Gene Age | 987 ( ENSG00000117479 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60779 |
| Gene Card | SLC19A2 |
| Uniprot ID | O60779 |
| Pfam | PF01770 |
| In ASD | no |
| Allosteric Prediction | no (-0.751998715) |
| Ortholog in Animals | Alpaca_ SLC19A2 ( ortholog_one2one ) Dog_ SLC19A2 ( ortholog_one2one ) GuineaPig_ SLC19A2 ( ortholog_one2one ) Macaque_ SLC19A2 ( ortholog_one2one ) Mouse_ Slc19a2 ( ortholog_one2one ) Pig_ SLC19A2 ( ortholog_one2one ) Rat_ Slc19a2 ( ortholog_one2one ) Rabbit_ SLC19A2 ( ortholog_one2one ) |
| Ohnologs | SLC19A3 |
| Paralogs | SLC19A3, SLC19A1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung. {ECO:0000269|PubMed:10391222, ECO:0000269|PubMed:10542220}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs761957186 rs28937595 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:10391222, ECO:0000305|PubMed:10542220}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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