| Gene Information | |
|---|---|
| Gene Name | PPP1R16B |
| Organism | Homo sapiens (Human) |
| Gene Length | 567 |
| Protein Names | Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000101445 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q96T49 |
| Gene Card | PPP1R16B |
| Uniprot ID | Q96T49 |
| Pfam | PF12796 |
| In ASD | no |
| Allosteric Prediction | no (-0.914697519) |
| Ortholog in Animals | Alpaca_ PPP1R16B ( ortholog_one2one ) Dog_ PPP1R16B ( ortholog_one2one ) GuineaPig_ PPP1R16B ( ortholog_one2one ) Macaque_ PPP1R16B ( ortholog_one2one ) Mouse_ Ppp1r16b ( ortholog_one2one ) Pig_ PPP1R16B ( ortholog_one2one ) Rat_ Ppp1r16b ( ortholog_one2one ) Rabbit_ PPP1R16B ( ortholog_one2one ) |
| Ohnologs | PPP1R16A |
| Paralogs | PPP1R16A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18586956, ECO:0000269|PubMed:26497934}. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Nucleus {ECO:0000269|PubMed:18586956}. Cell projection {ECO:0000269|PubMed:25007873}. Note=Colocalizes with RPSA/LAMR1 in the cell membrane (PubMed:16263087). Localizes to the perinuclear region (By similarity). Colocalizes with PTEN at the tip of EC projections (PubMed:25007873). {ECO:0000250|UniProtKB:Q95N27, ECO:0000269|PubMed:16263087, ECO:0000269|PubMed:25007873}. |
| Mouse PG classification | NA |
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