Gene Information
Gene NameALDH3A2
OrganismHomo sapiens (Human)
Gene Length485
Protein NamesAldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase)
Target Namefatty aldehyde dehydrogenase
Target TypeSuccessful target
Gene Age1488 ( ENSG00000072210 )
Evolutionary StageEuk+Bac
AlphaFoldDBP51648
Gene CardALDH3A2
Uniprot IDP51648
PfamPF00171
In ASDno
Allosteric Predictionno (-0.233192277)
Ortholog in AnimalsAlpaca_ ALDH3A2 ( ortholog_one2one )
GuineaPig_ ALDH3A2 ( ortholog_one2one )
Macaque_ ALDH3A2 ( ortholog_one2one )
Mouse_ Aldh3a2 ( ortholog_one2one )
Pig_ ALDH3A2 ( ortholog_one2one )
Rat_ Aldh3a2 ( ortholog_one2one )
Rabbit_ ALDH3A2 ( ortholog_one2one )
OhnologsALDH3B1, ALDH3B2
ParalogsALDH7A1, ALDH1B1, ALDH1A1, ALDH3B1, ALDH3B2, ALDH3A1, ALDH2, ALDH9A1, ALDH1A2, ALDH6A1, ALDH5A1, ALDH1L1, ALDH1A3, ALDH1L2, ALDH8A1, ALDH4A1, ALDH16A1
TissueNA
Tissue SpecificityDetected in liver (at protein level). {ECO:0000269|PubMed:9133646}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4QGK  (X-ray  2.10A  ) 
DBSNP rs72547556  rs72547558  rs72547559  rs72547560  rs72547562  rs72547563  rs72547564  rs72547565  rs72547566  rs72547567  rs72547568  rs72547569  rs72547570  rs72547571  rs72547572  rs72547573  rs72547575  rs778115541  rs72547576  rs768290318  rs67939114 
Subcellular location [CC]Microsome membrane {ECO:0000269|PubMed:9133646};
Single-pass membrane protein {ECO:0000305|PubMed:25047030, ECO:0000305|PubMed:9133646}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:9133646};
Single-pass membrane protein {ECO:0000305|PubMed:25047030, ECO:0000305|PubMed:9133646};
Cytoplasmic side {ECO:0000250|UniProtKB:P30839}.
Mouse PG classificationLPG
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