| Gene Information | |
|---|---|
| Gene Name | JMJD2C |
| Organism | Homo sapiens (Human) |
| Gene Length | 1056 |
| Protein Names | Lysine-specific demethylase 4C (EC 1.14.11.66) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C) ([histone H3]-trimethyl-L-lysine(9) demethylase 4C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H3R0 |
| Gene Card | KDM4C |
| Uniprot ID | Q9H3R0 |
| Pfam | PF02373; PF02375; PF18104 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Overexpressed in several esophageal squamous cell carcinomas (ESCs). {ECO:0000269|PubMed:10987278}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XDP (X-ray 1.56A ) 2XML (X-ray 2.55A ) 4XDO (X-ray 1.97A ) 4XDP (X-ray 2.07A ) 5FJH (X-ray 2.10A ) 5FJK (X-ray 1.66A ) 5KR7 (X-ray 1.90A ) |
| DBSNP | rs7864351 rs2296067 rs35826653 rs35389625 rs1407856 rs1417290 rs913588 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}. |
| Mouse PG classification | NA |
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