Home
Genetic Feature
Search By Gene Name
Search By Disease Name
Evolutionary Feature
Search By Gene Name
Search By Ohnolog
Search By Ortholog
Allosteric Protein
Drug
Browse
Browse By Gene Name
Browse By Drug Name
Browse By Disease Name
Browse By Evolutionary Stage
Help
Download
Gene Information
Gene Name
JMJD2A
Organism
Homo sapiens (Human)
Gene Length
1064
Protein Names
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
O75164
Gene Card
KDM4A
Uniprot ID
O75164
Pfam
PF02373; PF02375; PF18104
In ASD
yes
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
Ubiquitous. {ECO:0000269|PubMed:15927959}.
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.005405(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
2GF7
(X-ray
2.20A
)
2GFA
(X-ray
2.10A
)
2GP3
(X-ray
2.35A
)
2GP5
(X-ray
2.28A
)
2OQ6
(X-ray
2.00A
)
2OQ7
(X-ray
2.15A
)
2OS2
(X-ray
2.30A
)
2OT7
(X-ray
2.13A
)
2OX0
(X-ray
1.95A
)
2P5B
(X-ray
1.99A
)
2PXJ
(X-ray
2.00A
)
2Q8C
(X-ray
2.05A
)
2Q8D
(X-ray
2.29A
)
2Q8E
(X-ray
2.05A
)
2QQR
(X-ray
1.80A
)
2QQS
(X-ray
2.82A
)
2VD7
(X-ray
2.25A
)
2WWJ
(X-ray
2.60A
)
2YBK
(X-ray
2.40A
)
2YBP
(X-ray
2.02A
)
2YBS
(X-ray
2.32A
)
3NJY
(X-ray
2.60A
)
3PDQ
(X-ray
1.99A
)
3RVH
(X-ray
2.25A
)
3U4S
(X-ray
2.15A
)
4AI9
(X-ray
2.25A
)
4BIS
(X-ray
2.49A
)
4GD4
(X-ray
2.33A
)
4URA
(X-ray
2.23A
)
4V2V
(X-ray
2.00A
)
4V2W
(X-ray
1.81A
)
5A7N
(X-ray
2.39A
)
5A7O
(X-ray
2.15A
)
5A7P
(X-ray
2.28A
)
5A7Q
(X-ray
2.00A
)
5A7S
(X-ray
2.20A
)
5A7W
(X-ray
2.27A
)
5A80
(X-ray
2.28A
)
5ANQ
(X-ray
2.00A
)
5D6W
(X-ray
1.99A
)
5D6X
(X-ray
2.15A
)
5D6Y
(X-ray
2.29A
)
5F2S
(X-ray
2.08A
)
5F2W
(X-ray
2.60A
)
5F32
(X-ray
2.05A
)
5F37
(X-ray
2.22A
)
5F39
(X-ray
2.65A
)
5F3C
(X-ray
2.06A
)
5F3E
(X-ray
2.16A
)
5F3G
(X-ray
2.50A
)
5F3I
(X-ray
2.24A
)
5F5I
(X-ray
2.63A
)
5FPV
(X-ray
2.44A
)
5FWE
(X-ray
2.05A
)
5FY8
(X-ray
2.34A
)
5FYC
(X-ray
2.26A
)
5FYH
(X-ray
2.35A
)
5FYI
(X-ray
2.10A
)
5LY1
(X-ray
2.50A
)
5LY2
(X-ray
2.43A
)
5TVR
(X-ray
2.09A
)
5TVS
(X-ray
2.75A
)
5VAR
(X-ray
1.83A
)
5VGI
(X-ray
2.07A
)
5VMP
(X-ray
2.48A
)
6CG1
(X-ray
2.16A
)
6CG2
(X-ray
2.34A
)
6G5W
(X-ray
1.83A
)
6G5X
(X-ray
1.78A
)
6H4O
(X-ray
2.25A
)
6H4P
(X-ray
2.19A
)
6H4Q
(X-ray
2.31A
)
6H4R
(X-ray
2.14A
)
6H4S
(X-ray
2.45A
)
6H4T
(X-ray
2.38A
)
6H4U
(X-ray
2.21A
)
6H4V
(X-ray
2.15A
)
6H4W
(X-ray
2.81A
)
6H4X
(X-ray
2.34A
)
6H4Y
(X-ray
2.38A
)
6H8P
(X-ray
1.98A
)
6HGT
(X-ray
2.33A
)
7D4A
(X-ray
2.20A
)
7EQV
(X-ray
2.60A
)
DBSNP
rs586339
rs12759032
Subcellular location [CC]
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Mouse PG classification
NA
click here
to return to the previous page
