| Gene Information | |
|---|---|
| Gene Name | IFIT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 482 |
| Protein Names | Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152778 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q13325 |
| Gene Card | IFIT5 |
| Uniprot ID | Q13325 |
| Pfam | PF07719; PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-0.743615884) |
| Ortholog in Animals | Alpaca_ IFIT5 ( ortholog_one2one ) GuineaPig_ IFIT5 ( ortholog_one2one ) Macaque_ IFIT5 ( ortholog_one2one ) Pig_ IFIT5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFIT2, IFIT3, IFIT1B, IFIT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ZGQ (X-ray 2.20A ) 4HOQ (X-ray 2.07A ) 4HOR (X-ray 1.86A ) 4HOS (X-ray 2.00A ) 4HOT (X-ray 2.50A ) 4J0U (X-ray 1.97A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, ruffle membrane {ECO:0000269|PubMed:23317505}. Note=Colocalized with RIGI at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface. |
| Mouse PG classification | NA |
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