| Gene Information | |
|---|---|
| Gene Name | JM21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1215 |
| Protein Names | Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UBN7 |
| Gene Card | HDAC6 |
| Uniprot ID | Q9UBN7 |
| Pfam | PF00850; PF02148 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001142(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3C5K (X-ray 1.55A ) 3GV4 (X-ray 1.72A ) 3PHD (X-ray 3.00A ) 5B8D (X-ray 1.05A ) 5EDU (X-ray 2.79A ) 5KH3 (X-ray 1.60A ) 5KH7 (X-ray 1.70A ) 5KH9 (X-ray 1.07A ) 5WBN (X-ray 1.64A ) 5WPB (X-ray 1.55A ) 6CE6 (X-ray 1.60A ) 6CE8 (X-ray 1.55A ) 6CEA (X-ray 1.60A ) 6CEC (X-ray 1.55A ) 6CED (X-ray 1.70A ) 6CEE (X-ray 1.55A ) 6CEF (X-ray 1.80A ) 7ZYU (X-ray 2.43A ) |
| DBSNP | rs1127346 rs151130423 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12024216, ECO:0000269|PubMed:24687993}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12024216}. Nucleus {ECO:0000250|UniProtKB:Q9Z2V5}. Perikaryon {ECO:0000250|UniProtKB:Q9Z2V5}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Z2V5}. Cell projection, axon {ECO:0000250|UniProtKB:Q9Z2V5}. Cell projection, cilium {ECO:0000269|PubMed:17604723}. Note=It is mainly cytoplasmic, where it is associated with microtubules. {ECO:0000269|PubMed:12024216}. |
| Mouse PG classification | NA |
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