| Gene Information | |
|---|---|
| Gene Name | GCLC |
| Organism | Homo sapiens (Human) |
| Gene Length | 637 |
| Protein Names | Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) |
| Target Name | glutamate--cysteine ligase catalytic subunit |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000001084 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P48506 |
| Gene Card | GCLC |
| Uniprot ID | P48506 |
| Pfam | PF03074 |
| In ASD | no |
| Allosteric Prediction | yes (1.176902122) |
| Ortholog in Animals | Alpaca_ GCLC ( ortholog_one2one ) Dog_ GCLC ( ortholog_one2one ) GuineaPig_ GCLC ( ortholog_one2one ) Macaque_ GCLC ( ortholog_one2one ) Mouse_ Gclc ( ortholog_one2one ) Pig_ GCLC ( ortholog_one2one ) Rat_ Gclc ( ortholog_one2one ) Rabbit_ GCLC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2066512 rs760031222 rs121907946 rs17883718 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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