| Gene Information | |
|---|---|
| Gene Name | JAML |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000160593 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q86YT9 |
| Gene Card | JAML |
| Uniprot ID | Q86YT9 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.529976697) |
| Ortholog in Animals | Alpaca_ JAML ( ortholog_one2one ) Dog_ JAML ( ortholog_one2one ) Macaque_ JAML ( ortholog_one2one ) Pig_ JAML ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MPZL1, MPZ, MPZL3, MPZL2, SCN2B, SCN4B |
| Tissue | adipose.tissue, lung, ovary, sigmoid.colon, spleen, whole.blood |
| Tissue Specificity | Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus. Preferentially expressed by mature leukocytes (at protein level). {ECO:0000269|PubMed:12869515, ECO:0000269|PubMed:18948633, ECO:0000269|PubMed:19064666}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17121881 rs1793174 rs2298831 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12869515}; Single-pass type I membrane protein {ECO:0000269|PubMed:12869515}. Cell junction {ECO:0000269|PubMed:12869515}. Note=Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515). |
| Mouse PG classification | NA |
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