Gene Information
Gene NameJAM1
OrganismHomo sapiens (Human)
Gene Length299
Protein NamesJunctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9Y624
Gene CardF11R
Uniprot IDQ9Y624
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in endothelium, epithelium and leukocytes (at protein level). {ECO:0000269|PubMed:11812992}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1NBQ  (X-ray  2.90A  3EOY  (X-ray  3.40A  3TSZ  (X-ray  2.50A  4ODB  (X-ray  3.20A 
DBSNP NA 
Subcellular location [CC]Cell junction, tight junction {ECO:0000269|PubMed:11171323}. Cell membrane {ECO:0000269|PubMed:11171323};
Single-pass type I membrane protein {ECO:0000269|PubMed:11171323}. Note=Localized at tight junctions of both epithelial and endothelial cells. {ECO:0000269|PubMed:11171323}.
Mouse PG classificationNA
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