| Gene Information | |
|---|---|
| Gene Name | JAG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1238 |
| Protein Names | Protein jagged-2 (Jagged2) (hJ2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000184916 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y219 |
| Gene Card | JAG2 |
| Uniprot ID | Q9Y219 |
| Pfam | PF01414; PF00008; PF07645; PF12661; PF07657 |
| In ASD | no |
| Allosteric Prediction | no (-0.531530738) |
| Ortholog in Animals | Alpaca_ JAG2 ( ortholog_one2one ) Dog_ JAG2 ( ortholog_one2one ) GuineaPig_ JAG2 ( ortholog_one2one ) Macaque_ JAG2 ( ortholog_one2one ) Mouse_ Jag2 ( ortholog_one2one ) Pig_ JAG2 ( ortholog_one2one ) Rat_ Jag2 ( ortholog_one2one ) |
| Ohnologs | JAG1 |
| Paralogs | NOTCH4, JAG1, DNER, DLL4, DLL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MW5 (X-ray 2.70A ) 5MW7 (X-ray 2.80A ) 5MWF (X-ray 2.80A ) |
| DBSNP | rs1057744 rs9972231 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |