| Gene Information | |
|---|---|
| Gene Name | ACTL8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Actin-like protein 8 (Cancer/testis antigen 57) (CT57) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000117148 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H568 |
| Gene Card | ACTL8 |
| Uniprot ID | Q9H568 |
| Pfam | PF00022 |
| In ASD | no |
| Allosteric Prediction | no (-1.219324571) |
| Ortholog in Animals | Alpaca_ ACTL8 ( ortholog_one2one ) Dog_ ACTL8 ( ortholog_one2one ) GuineaPig_ ACTL8 ( ortholog_one2one ) Macaque_ ACTL8 ( ortholog_one2one ) Pig_ ACTL8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in testis and pancreas. Weak expression in placenta. {ECO:0000269|PubMed:15905330}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs694214 rs3795322 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. |
| Mouse PG classification | NA |
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