Gene Information
Gene NameIVL
OrganismHomo sapiens (Human)
Gene Length585
Protein NamesInvolucrin
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000163207 )
Evolutionary StageEumetazoa
AlphaFoldDBP07476
Gene CardIVL
Uniprot IDP07476
PfamPF00904; PF10583
In ASDno
Allosteric Predictionno (-0.477312915)
Ortholog in AnimalsAlpaca_ IVL ( ortholog_one2one )
Macaque_ IVL ( ortholog_one2one )
Pig_ IVL ( ortholog_one2one )
Rat_ Ivl ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissueesophagus, esophagus.mucosa, lower.leg.skin, suprapubic.skin, vagina
Tissue SpecificityKeratinocytes of epidermis and other stratified squamous epithelia.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2229496  rs11205133  rs12035307  rs11807064  rs17855670  rs7520711  rs11205137  rs7545520 
Subcellular location [CC]Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Mouse PG classificationNA
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