| Gene Information | |
|---|---|
| Gene Name | MTIF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000085760 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P46199 |
| Gene Card | MTIF2 |
| Uniprot ID | P46199 |
| Pfam | PF00009; PF11987 |
| In ASD | no |
| Allosteric Prediction | no (-0.577290223) |
| Ortholog in Animals | Alpaca_ MTIF2 ( ortholog_one2one ) Dog_ MTIF2 ( ortholog_one2one ) GuineaPig_ MTIF2 ( ortholog_one2one ) Macaque_ MTIF2 ( ortholog_one2one ) Mouse_ Mtif2 ( ortholog_one2one ) Pig_ MTIF2 ( ortholog_one2one ) Rat_ Mtif2 ( ortholog_one2one ) Rabbit_ MTIF2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, EIF5B, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GFM1, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined. Highest level in skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002119(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6GAW (EM 3.20A ) 6GAZ (EM 3.10A ) 6GB2 (EM 3.20A ) 6RW5 (EM 3.14A ) 7PO2 (EM 3.09A ) |
| DBSNP | rs1056445 rs11357 |
| Subcellular location [CC] | Mitochondrion. |
| Mouse PG classification | NA |
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