Gene Information
Gene NameITPKB
OrganismHomo sapiens (Human)
Gene Length946
Protein NamesInositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000143772 )
Evolutionary StageOpisthokonta
AlphaFoldDBP27987
Gene CardITPKB
Uniprot IDP27987
PfamPF03770
In ASDno
Allosteric Predictionyes (0.381780297)
Ortholog in AnimalsAlpaca_ ITPKB ( ortholog_one2one )
Dog_ ITPKB ( ortholog_one2one )
GuineaPig_ ITPKB ( ortholog_one2one )
Macaque_ ITPKB ( ortholog_one2one )
Mouse_ Itpkb ( ortholog_one2one )
Rat_ Itpkb ( ortholog_one2one )
Rabbit_ ITPKB ( ortholog_one2one )
OhnologsITPKC, ITPKA
ParalogsIP6K1, IPMK, IP6K2, IP6K3, ITPKA, ITPKC
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3754413  rs6667260  rs708776 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Endoplasmic reticulum {ECO:0000269|PubMed:12747803}.
Mouse PG classificationNA
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