| Gene Information | |
|---|---|
| Gene Name | ITIH3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 890 |
| Protein Names | Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP) |
| Target Name | inter-alpha-trypsin inhibitor heavy chain h3 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000162267 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q06033 |
| Gene Card | ITIH3 |
| Uniprot ID | Q06033 |
| Pfam | PF06668; PF08487; PF00092 |
| In ASD | no |
| Allosteric Prediction | yes (0.124115011) |
| Ortholog in Animals | Alpaca_ ITIH3 ( ortholog_one2one ) Dog_ ITIH3 ( ortholog_one2one ) GuineaPig_ ITIH3 ( ortholog_one2one ) Macaque_ ITIH3 ( ortholog_one2one ) Mouse_ Itih3 ( ortholog_one2one ) Pig_ ITIH3 ( ortholog_one2one ) Rat_ Itih3 ( ortholog_one2one ) Rabbit_ ITIH3 ( ortholog_one2one ) |
| Ohnologs | ITIH6, ITIH5, ITIH2 |
| Paralogs | VWA5A, ITIH4, VWA5B2, ITIH5, VWA5B1, ITIH2, VWA3B, PARP4, ITIH6, ITIH1, VWA3A |
| Tissue | liver, artery, brain, cervix, dura.mater, ovary, penis, spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3617 rs35271262 rs60805548 rs9883888 rs2710330 rs2710329 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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