| Gene Information | |
|---|---|
| Gene Name | WNT16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 365 |
| Protein Names | Protein Wnt-16 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000002745 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UBV4 |
| Gene Card | WNT16 |
| Uniprot ID | Q9UBV4 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-0.999914884) |
| Ortholog in Animals | Alpaca_ WNT16 ( ortholog_one2one ) Dog_ WNT16 ( ortholog_one2one ) GuineaPig_ WNT16 ( ortholog_one2one ) Macaque_ WNT16 ( ortholog_one2one ) Mouse_ Wnt16 ( ortholog_one2one ) Pig_ WNT16 ( ortholog_one2one ) Rat_ Wnt16 ( ortholog_one2one ) Rabbit_ WNT16 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | WNT5A, WNT6, WNT3, WNT4, WNT2B, WNT2, WNT9B, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT7A, WNT10B, WNT1, WNT8A |
| Tissue | skin, pineal.gland |
| Tissue Specificity | Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2908004 rs2707466 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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