| Gene Information | |
|---|---|
| Gene Name | ITGB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 798 |
| Protein Names | Integrin beta-7 (Gut homing receptor beta subunit) |
| Target Name | integrin beta-7 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139626 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P26010 |
| Gene Card | ITGB7 |
| Uniprot ID | P26010 |
| Pfam | PF07974; PF08725; PF00362; PF17205 |
| In ASD | no |
| Allosteric Prediction | yes (0.183939877) |
| Ortholog in Animals | Alpaca_ ITGB7 ( ortholog_one2one ) Dog_ ITGB7 ( ortholog_one2one ) GuineaPig_ ITGB7 ( ortholog_one2one ) Macaque_ ITGB7 ( ortholog_one2one ) Mouse_ Itgb7 ( ortholog_one2one ) Pig_ ITGB7 ( ortholog_one2one ) Rat_ Itgb7 ( ortholog_one2one ) Rabbit_ ITGB7 ( ortholog_one2one ) |
| Ohnologs | ITGB2, ITGB8, ITGB6, ITGB1 |
| Paralogs | ITGB4, ITGB3, ITGB5, ITGB8, ITGB6, ITGB1, ITGB2, ITGBL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in a variety of leukocyte lines. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002990(Rat);0.057143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BRQ (X-ray 2.10A ) 3V4P (X-ray 3.15A ) 3V4V (X-ray 3.10A ) |
| DBSNP | rs11539433 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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