| Gene Information | |
|---|---|
| Gene Name | ENTR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | Endosome-associated-trafficking regulator 1 (Antigen NY-CO-3) (Serologically defined colon cancer antigen 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165689 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96C92 |
| Gene Card | ENTR1 |
| Uniprot ID | Q96C92 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.44770192) |
| Ortholog in Animals | Alpaca_ ENTR1 ( ortholog_one2one ) Dog_ ENTR1 ( ortholog_one2one ) GuineaPig_ ENTR1 ( ortholog_one2one ) Macaque_ ENTR1 ( ortholog_one2one ) Mouse_ Entr1 ( ortholog_one2one ) Pig_ ENTR1 ( ortholog_one2one ) Rat_ AABR07064502.1 ( ortholog_one2many ) Rat_ Entr1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the colon (at protein level). {ECO:0000269|PubMed:23108400}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7047681 rs17851182 rs3812577 rs1131992 rs17855450 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:A2AIW0}. Early endosome {ECO:0000269|PubMed:23108400}. Endosome {ECO:0000269|PubMed:25278552}. Recycling endosome {ECO:0000269|PubMed:23108400}. Midbody {ECO:0000269|PubMed:23108400}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23108400, ECO:0000269|PubMed:27767179}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:27767179}. Note=Colocalizes in a WASHC2-dependent manner with the retromer CSC complex at endosomes (PubMed:25278552). During cytokinesis colocalized with PTPN13 at the midbody (PubMed:23108400). Colocalizes with IFT88 and gamma-tubulin at the basal body of primary cilia (PubMed:27767179). Colocalizes with IFT88 and pericentrin at the centrosome (PubMed:27767179). {ECO:0000269|PubMed:23108400, ECO:0000269|PubMed:25278552, ECO:0000269|PubMed:27767179}. |
| Mouse PG classification | NA |
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