| Gene Information | |
|---|---|
| Gene Name | ITGA11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1188 |
| Protein Names | Integrin alpha-11 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000137809 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UKX5 |
| Gene Card | ITGA11 |
| Uniprot ID | Q9UKX5 |
| Pfam | PF01839; PF08441; PF00092 |
| In ASD | no |
| Allosteric Prediction | no (-0.185137667) |
| Ortholog in Animals | Alpaca_ ITGA11 ( ortholog_one2one ) Dog_ ITGA11 ( ortholog_one2one ) GuineaPig_ ITGA11 ( ortholog_one2one ) Macaque_ ITGA11 ( ortholog_one2one ) Mouse_ Itga11 ( ortholog_one2one ) Pig_ ITGA11 ( ortholog_one2one ) Rat_ Itga11 ( ortholog_one2one ) Rabbit_ ITGA11 ( ortholog_one2one ) |
| Ohnologs | ITGAL, ITGAX, ITGAD, ITGAM, ITGA10, ITGA2, ITGA1 |
| Paralogs | ITGA10, ITGA4, ITGAX, ITGAE, ITGA2, ITGAD, ITGA5, ITGA6, ITGAV, ITGA7, ITGA8, ITGAL, ITGA3, ITGA2B, ITGA1, ITGAM, ITGA9 |
| Tissue | endometrium, smooth.muscle, aorta |
| Tissue Specificity | According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. {ECO:0000269|PubMed:10464311}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2306022 rs2306024 rs7168069 rs2271725 rs4777035 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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