| Gene Information | |
|---|---|
| Gene Name | ISX |
| Organism | Homo sapiens (Human) |
| Gene Length | 245 |
| Protein Names | Intestine-specific homeobox (RAX-like homeobox) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000175329 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q2M1V0 |
| Gene Card | ISX |
| Uniprot ID | Q2M1V0 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | yes (0.122168199) |
| Ortholog in Animals | Alpaca_ ISX ( ortholog_one2one ) Dog_ ISX ( ortholog_one2one ) Macaque_ ISX ( ortholog_one2one ) Mouse_ Isx ( ortholog_one2one ) Pig_ ISX ( ortholog_one2one ) Rat_ Isx ( ortholog_one2one ) Rabbit_ ISX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | colon, duodenum, small.intestine, rectum, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs361863 rs362090 rs8140287 rs7291048 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | NA |
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