| Gene Information | |
|---|---|
| Gene Name | ISM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 571 |
| Protein Names | Isthmin-2 (Thrombospondin and AMOP domain-containing isthmin-like protein 1) (Thrombospondin type-1 domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100593 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6H9L7 |
| Gene Card | ISM2 |
| Uniprot ID | Q6H9L7 |
| Pfam | PF03782; PF00090 |
| In ASD | no |
| Allosteric Prediction | no (-1.395927331) |
| Ortholog in Animals | Alpaca_ ISM2 ( ortholog_one2one ) Dog_ ISM2 ( ortholog_one2one ) Macaque_ ISM2 ( ortholog_one2one ) Mouse_ Ism2 ( ortholog_one2one ) Rat_ Ism2 ( ortholog_one2one ) |
| Ohnologs | ISM1 |
| Paralogs | NA |
| Tissue | placenta |
| Tissue Specificity | Expressed at high levels in the placenta and at moderate levels in the pancreas, kidney, heart, liver, lung, brain and skeletal muscle. {ECO:0000269|PubMed:15194193}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3742728 rs11850175 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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