| Gene Information | |
|---|---|
| Gene Name | ISLR |
| Organism | Homo sapiens (Human) |
| Gene Length | 428 |
| Protein Names | Immunoglobulin superfamily containing leucine-rich repeat protein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000129009 ) 3 ( ENSG00000288508 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14498 |
| Gene Card | ISLR |
| Uniprot ID | O14498 |
| Pfam | PF07679; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.694307513) |
| Ortholog in Animals | Alpaca_ ISLR ( ortholog_one2one ) Dog_ ISLR ( ortholog_one2one ) GuineaPig_ ISLR ( ortholog_one2one ) Macaque_ ISLR ( ortholog_one2one ) Mouse_ Islr ( ortholog_one2one ) Pig_ ISLR ( ortholog_one2one ) Rat_ Islr ( ortholog_one2one ) Rabbit_ ISLR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRRN4CL, ISLR2, LRRN4 |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues including retina, heart, skeletal muscle, prostate, ovary, small intestine, thyroid, adrenal cortex, testis, stomach and spinal cord. {ECO:0000269|PubMed:10512678, ECO:0000269|PubMed:9325048}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs376998994 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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