| Gene Information | |
|---|---|
| Gene Name | ISL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 349 |
| Protein Names | Insulin gene enhancer protein ISL-1 (Islet-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000016082 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P61371 |
| Gene Card | ISL1 |
| Uniprot ID | P61371 |
| Pfam | PF00046; PF00412 |
| In ASD | no |
| Allosteric Prediction | yes (0.015121513) |
| Ortholog in Animals | Alpaca_ ISL1 ( ortholog_one2one ) Dog_ ISL1 ( ortholog_one2one ) GuineaPig_ ISL1 ( ortholog_one2one ) Macaque_ ISL1 ( ortholog_one2one ) Mouse_ Isl1 ( ortholog_one2one ) Pig_ ISL1 ( ortholog_one2one ) Rat_ Isl1 ( ortholog_one2one ) Rabbit_ ISL1 ( ortholog_one2one ) |
| Ohnologs | LHX2, ISL2 |
| Paralogs | ISL2 |
| Tissue | cervix, penis, placenta, prostate, seminal.vesicle, brain |
| Tissue Specificity | Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. {ECO:0000269|PubMed:7907017}. |
| Pharmacological Animal Models | 0.044130(Chimpanzee);0.079146(Mouse);0.003990(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P61372}. |
| Mouse PG classification | NA |
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