| Gene Information | |
|---|---|
| Gene Name | UFD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1302 |
| Protein Names | Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (Homozygously deleted in neuroblastoma 1) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95155 |
| Gene Card | UBE4B |
| Uniprot ID | O95155 |
| Pfam | PF04564; PF10408 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in differentiated myotubes (at protein level) (PubMed:17369820). Highest expression in ovary, testis, heart and skeletal muscle (PubMed:11802788). Expression is low in colon, thymus and peripheral blood leukocytes (PubMed:11802788). Almost undetectable in lung and spleen (PubMed:11802788). {ECO:0000269|PubMed:11802788, ECO:0000269|PubMed:17369820}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KRE (NMR - ) 3L1X (X-ray 2.60A ) 3L1Z (X-ray 3.17A ) 5O75 (X-ray 1.48A ) |
| DBSNP | rs17034499 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17369820}. Nucleus {ECO:0000250|UniProtKB:Q9ES00}. |
| Mouse PG classification | NA |
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