| Gene Information | |
|---|---|
| Gene Name | ISG20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 181 |
| Protein Names | Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Estrogen-regulated transcript 45 protein) (Promyelocytic leukemia nuclear body-associated protein ISG20) |
| Target Name | interferon-stimulated gene 20 kda protein |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000172183 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96AZ6 |
| Gene Card | ISG20 |
| Uniprot ID | Q96AZ6 |
| Pfam | PF00929 |
| In ASD | no |
| Allosteric Prediction | no (-0.447600539) |
| Ortholog in Animals | Alpaca_ ISG20 ( ortholog_one2one ) Dog_ ISG20 ( ortholog_one2one ) GuineaPig_ ISG20 ( ortholog_one2one ) Macaque_ ISG20 ( ortholog_one2one ) Mouse_ Isg20 ( ortholog_one2one ) Pig_ ISG20 ( ortholog_one2one ) Rat_ Isg20 ( ortholog_one2one ) Rabbit_ ISG20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AEN, REXO5, REXO4, ISG20L2, REXO1 |
| Tissue | appendix, gall.bladder, lung, spleen, whole.blood |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. {ECO:0000269|PubMed:9235947, ECO:0000269|PubMed:9569007}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WLJ (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body. |
| Mouse PG classification | NA |
| click here to return to the previous page | |