| Gene Information | |
|---|---|
| Gene Name | CNDP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 475 |
| Protein Names | Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000133313 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96KP4 |
| Gene Card | CNDP2 |
| Uniprot ID | Q96KP4 |
| Pfam | PF07687; PF01546 |
| In ASD | no |
| Allosteric Prediction | yes (0.301089535) |
| Ortholog in Animals | Alpaca_ CNDP2 ( ortholog_one2one ) Dog_ CNDP2 ( ortholog_one2one ) GuineaPig_ CNDP2 ( ortholog_one2one ) Mouse_ Cndp2 ( ortholog_one2one ) Pig_ CNDP2 ( ortholog_one2one ) Rat_ Cndp2 ( ortholog_one2one ) Rabbit_ CNDP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACY1, PM20D1, CNDP1 |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:24395568}.; [Isoform 2]: Broadly expressed in fetal tissues. Expressed in adult liver and placenta. {ECO:0000269|PubMed:17121880}. |
| Pharmacological Animal Models | 0.030997(Chimpanzee);NULL(Mouse);0.006101(Rat);0.020513(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4RUH (X-ray 2.25A ) |
| DBSNP | rs2278161 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:17121880}. |
| Mouse PG classification | NA |
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