| Gene Information | |
|---|---|
| Gene Name | IRLB |
| Organism | Homo sapiens (Human) |
| Gene Length | 1863 |
| Protein Names | C-myc promoter-binding protein (DENN domain-containing protein 4A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q7Z401 |
| Gene Card | DENND4A |
| Uniprot ID | Q7Z401 |
| Pfam | PF03455; PF02141; PF03456 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner. {ECO:0000269|PubMed:12906859}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17854146 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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