Gene Information
Gene NameSERPINA11
OrganismHomo sapiens (Human)
Gene Length417
Protein NamesSerpin A9 (Centerin) (Germinal center B-cell-expressed transcript 1 protein)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000186910 )
Evolutionary StageMammalia
AlphaFoldDBQ86WD7
Gene CardSERPINA9
Uniprot IDQ86WD7
PfamPF00079
In ASDno
Allosteric Predictionno (-0.83301224)
Ortholog in AnimalsAlpaca_ SERPINA11 ( ortholog_one2one )
Dog_ SERPINA11 ( ortholog_one2one )
GuineaPig_ SERPINA11 ( ortholog_one2one )
Macaque_ SERPINA11 ( ortholog_one2one )
Mouse_ Serpina11 ( ortholog_one2one )
Pig_ SERPINA11 ( ortholog_one2one )
Rat_ Serpina11 ( ortholog_one2one )
OhnologsSERPINB2
ParalogsSERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINB2
Tissueliver
Tissue SpecificityHighly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. {ECO:0000269|PubMed:12819018, ECO:0000269|PubMed:17447896, ECO:0000269|PubMed:17898315, ECO:0000269|PubMed:18550480}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs4905204  rs17090921  rs28583900  rs28618118  rs11628722 
Subcellular location [CC][Isoform 1]: Secreted.;
[Isoform 2]: Cytoplasm {ECO:0000305}.;
[Isoform 3]: Cytoplasm {ECO:0000305}.;
[Isoform 4]: Cytoplasm {ECO:0000305}.;
[Isoform 5]: Cytoplasm {ECO:0000305}.;
[Isoform 6]: Cytoplasm {ECO:0000305}.;
[Isoform 7]: Membrane {ECO:0000305};
Single-pass type II membrane protein {ECO:0000305}.
Mouse PG classificationNA
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