| Gene Information | |
|---|---|
| Gene Name | TNS4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 715 |
| Protein Names | Tensin-4 (C-terminal tensin-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000131746 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IZW8 |
| Gene Card | TNS4 |
| Uniprot ID | Q8IZW8 |
| Pfam | PF08416; PF00017 |
| In ASD | no |
| Allosteric Prediction | no (-1.173137948) |
| Ortholog in Animals | Alpaca_ TNS4 ( ortholog_one2one ) Dog_ TNS4 ( ortholog_one2one ) GuineaPig_ TNS4 ( ortholog_one2one ) Macaque_ TNS4 ( ortholog_one2one ) Mouse_ Tns4 ( ortholog_one2one ) Pig_ TNS4 ( ortholog_one2one ) Rat_ Tns4 ( ortholog_one2one ) Rabbit_ TNS4 ( ortholog_one2one ) |
| Ohnologs | TNS3 |
| Paralogs | TNS2 |
| Tissue | esophagus, salivary.gland, skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Prostate and placenta. Down regulated in prostate cancer. {ECO:0000269|PubMed:12154022}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3764424 rs33923045 rs2290207 rs148022611 |
| Subcellular location [CC] | Cell junction, focal adhesion {ECO:0000269|PubMed:12154022}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12154022}. |
| Mouse PG classification | NA |
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