Gene Information | |
---|---|
Gene Name | IRG1 |
Organism | Homo sapiens (Human) |
Gene Length | 481 |
Protein Names | Cis-aconitate decarboxylase (CAD) (EC 4.1.1.6) (Aconitate decarboxylase) (Aconitate decarboxylase 1) (Cis-aconitic acid decarboxylase) (Immune-responsive gene 1 protein) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | A6NK06 |
Gene Card | ACOD1 |
Uniprot ID | A6NK06 |
Pfam | PF03972; PF19305 |
In ASD | no |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Expressed in LPS-tolerized macrophages (at protein level). Expressed in peripheral blood mononuclear cells (PBMCs), microglia and macrophage cells. {ECO:0000269|PubMed:23609450, ECO:0000269|PubMed:23610393}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 6R6U (X-ray 1.71A ) |
DBSNP | rs767323284 rs1471882722 rs1018207074 rs1289708092 rs755737247 |
Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:P54987}. |
Mouse PG classification | NA |
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