Gene Information
Gene NameEIF3F
OrganismHomo sapiens (Human)
Gene Length357
Protein NamesEukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)
Target Nameeukaryotic translation initiation factor 3 subunit f
Target TypeNA
Gene Age>4290 ( ENSG00000175390 )
Evolutionary StageEukaryota
AlphaFoldDBO00303
Gene CardEIF3F
Uniprot IDO00303
PfamPF01398; PF13012
In ASDno
Allosteric Predictionyes (0.239307018)
Ortholog in AnimalsAlpaca_ EIF3F ( ortholog_one2one )
Dog_ EIF3F ( ortholog_one2one )
GuineaPig_ EIF3F ( ortholog_one2one )
Macaque_ EIF3F ( ortholog_one2one )
Mouse_ Eif3f ( ortholog_one2one )
Pig_ EIF3F ( ortholog_one2one )
Rat_ Eif3f ( ortholog_one2one )
Rabbit_ EIF3F ( ortholog_one2one )
OhnologsNA
ParalogsCOPS6, PSMD7
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.072338(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3J8B  (EM  -  )  3J8C  (EM  -  )  6YBD  (EM  3.30A  )  6ZMW  (EM  3.70A  )  6ZON  (EM  3.00A  )  6ZP4  (EM  2.90A  )  6ZVJ  (EM  3.80A  )  7A09  (EM  3.50A  )  7QP6  (EM  4.70A  )  7QP7  (EM  3.70A  ) 
DBSNP rs1043738  rs1044058  rs141976414 
Subcellular location [CC]Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03005}.
Mouse PG classificationNA
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