| Gene Information | |
|---|---|
| Gene Name | IREM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 290 |
| Protein Names | CMRF35-like molecule 1 (CLM-1) (CD300 antigen-like family member F) (Immune receptor expressed on myeloid cells 1) (IREM-1) (Immunoglobulin superfamily member 13) (IgSF13) (NK inhibitory receptor) (CD antigen CD300f) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TDQ1 |
| Gene Card | CD300LF |
| Uniprot ID | Q8TDQ1 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells. {ECO:0000269|PubMed:15184070, ECO:0000269|PubMed:15549731}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NMS (X-ray 2.60A ) |
| DBSNP | rs35489971 rs2034310 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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