Gene Information
Gene NameIREB1
OrganismHomo sapiens (Human)
Gene Length889
Protein NamesCytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Ferritin repressor protein) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP21399
Gene CardACO1
Uniprot IDP21399
PfamPF00330; PF00694
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2B3X  (X-ray  2.54A  2B3Y  (X-ray  1.85A 
DBSNP rs150373174  rs3814519  rs34630459 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:1281544}.
Mouse PG classificationNA
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