| Gene Information | |
|---|---|
| Gene Name | IRAK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 625 |
| Protein Names | Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000134070 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43187 |
| Gene Card | IRAK2 |
| Uniprot ID | O43187 |
| Pfam | PF00531; PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.330044315) |
| Ortholog in Animals | Alpaca_ IRAK2 ( ortholog_one2one ) Dog_ IRAK2 ( ortholog_one2one ) GuineaPig_ IRAK2 ( ortholog_one2one ) Macaque_ IRAK2 ( ortholog_one2one ) Mouse_ Irak2 ( ortholog_one2one ) Pig_ IRAK2 ( ortholog_one2one ) Rat_ Irak2 ( ortholog_one2one ) Rabbit_ IRAK2 ( ortholog_one2one ) |
| Ohnologs | IRAK3, IRAK1, IRAK4 |
| Paralogs | IRAK4, HASPIN, IRAK1, IRAK3 |
| Tissue | NA |
| Tissue Specificity | Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. {ECO:0000269|PubMed:9374458}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.368075(Rat);0.087724(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MOP (X-ray 3.40A ) |
| DBSNP | rs34945585 rs11465864 rs55898544 rs56053222 rs35060588 rs3844283 rs708035 rs11465927 rs56242986 rs9854688 rs55740652 rs11465930 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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