| Gene Information | |
|---|---|
| Gene Name | IRAG |
| Organism | Homo sapiens (Human) |
| Gene Length | 904 |
| Protein Names | Inositol 1,4,5-triphosphate receptor associated 1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) (Protein MRVI1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y6F6 |
| Gene Card | IRAG1 |
| Uniprot ID | Q9Y6F6 |
| Pfam | PF05781 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the colon, rectum, and cultured colonic smooth muscle. Detected in various cancer cell lines. {ECO:0000269|PubMed:10321731, ECO:0000269|PubMed:14729908}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4909945 rs34302310 rs2162044 rs35857561 rs34398944 |
| Subcellular location [CC] | Cytoplasm, perinuclear region. Sarcoplasmic reticulum {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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