| Gene Information | |
|---|---|
| Gene Name | CHST12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 414 |
| Protein Names | Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2) (Sulfotransferase Hlo) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000136213 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NRB3 |
| Gene Card | CHST12 |
| Uniprot ID | Q9NRB3 |
| Pfam | PF03567 |
| In ASD | no |
| Allosteric Prediction | no (-1.337069458) |
| Ortholog in Animals | Alpaca_ CHST12 ( ortholog_one2many ) Dog_ CHST12 ( ortholog_one2one ) Macaque_ CHST12 ( ortholog_one2one ) Mouse_ Chst12 ( ortholog_one2one ) Pig_ CHST12 ( ortholog_one2one ) Rat_ Chst12 ( ortholog_one2one ) |
| Ohnologs | CHST13 |
| Paralogs | CHST11, CHST8, CHST14, CHST10, CHST13, CHST9 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed a high level in spinal chord, heart, spleen, thyroid, pituitary gland, adrenal gland, peripheral blood leukocytes, thymus, lung, small intestine, fetal kidney, fetal spleen and fetal lung. {ECO:0000269|PubMed:10781601}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3735099 rs3735100 rs12536223 rs17132395 rs17132399 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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