| Gene Information | |
|---|---|
| Gene Name | MIHC |
| Organism | Homo sapiens (Human) |
| Gene Length | 604 |
| Protein Names | Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13489 |
| Gene Card | BIRC3 |
| Uniprot ID | Q13489 |
| Pfam | PF00653; PF00619 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.02439(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2UVL (X-ray 1.91A ) 3EB5 (X-ray 2.00A ) 3EB6 (X-ray 3.40A ) 3M0A (X-ray 2.61A ) 3M0D (X-ray 2.80A ) 7NK0 (X-ray 3.30A ) |
| DBSNP | rs2276113 rs12222256 rs17881197 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15665297}. Nucleus {ECO:0000269|PubMed:15665297}. |
| Mouse PG classification | NA |
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