| Gene Information | |
|---|---|
| Gene Name | IPO5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1097 |
| Protein Names | Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000065150 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00410 |
| Gene Card | IPO5 |
| Uniprot ID | O00410 |
| Pfam | PF02985; PF18808; PF18816; PF18829 |
| In ASD | no |
| Allosteric Prediction | no (-0.153545143) |
| Ortholog in Animals | Alpaca_ IPO5 ( ortholog_one2one ) Alpaca_ IPO5 ( ortholog_one2many ) Dog_ IPO5 ( ortholog_one2one ) Macaque_ IPO5 ( ortholog_one2one ) Mouse_ Ipo5 ( ortholog_one2one ) Pig_ IPO5 ( ortholog_one2one ) Rat_ Ipo5 ( ortholog_one2one ) Rabbit_ IPO5 ( ortholog_one2one ) |
| Ohnologs | RANBP6 |
| Paralogs | TNPO1, TNPO2, RANBP6, KPNB1, IPO4 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.010102(Chimpanzee);0.001000(Mouse);0.001407(Rat);0.014815(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6XTE (X-ray 2.27A ) 6XU2 (X-ray 2.83A ) |
| DBSNP | rs1053814 rs632729 rs484770 rs1804740 rs1804741 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Nucleus; nuclear rim. Found particularly in the nuclear rim and nucleolus. |
| Mouse PG classification | NA |
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