| Gene Information | |
|---|---|
| Gene Name | IPMK |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Inositol polyphosphate multikinase (EC 2.7.1.140) (EC 2.7.1.151) (EC 2.7.1.153) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000151151 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NFU5 |
| Gene Card | IPMK |
| Uniprot ID | Q8NFU5 |
| Pfam | PF03770 |
| In ASD | no |
| Allosteric Prediction | no (-0.988597661) |
| Ortholog in Animals | Alpaca_ IPMK ( ortholog_one2one ) GuineaPig_ IPMK ( ortholog_one2one ) Macaque_ IPMK ( ortholog_one2one ) Mouse_ Ipmk ( ortholog_one2one ) Pig_ IPMK ( ortholog_one2one ) Rat_ Ipmk ( ortholog_one2one ) Rabbit_ IPMK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IP6K1, IP6K2, ITPKB, IP6K3, ITPKA, ITPKC |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon. {ECO:0000269|PubMed:12223481}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5W2G (X-ray 1.80A ) 5W2H (X-ray 1.90A ) 5W2I (X-ray 1.60A ) 6E7F (X-ray 2.50A ) 6M88 (X-ray 1.90A ) 6M89 (X-ray 1.85A ) 6M8A (X-ray 1.75A ) 6M8B (X-ray 1.80A ) 6M8C (X-ray 1.80A ) 6M8D (X-ray 2.00A ) 6M8E (X-ray 2.00A ) |
| DBSNP | rs2275443 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12027805}. |
| Mouse PG classification | NA |
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