| Gene Information | |
|---|---|
| Gene Name | INTU |
| Organism | Homo sapiens (Human) |
| Gene Length | 942 |
| Protein Names | Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000164066 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9ULD6 |
| Gene Card | INTU |
| Uniprot ID | Q9ULD6 |
| Pfam | PF19031; PF19032; PF19033 |
| In ASD | no |
| Allosteric Prediction | no (-1.050227833) |
| Ortholog in Animals | Alpaca_ INTU ( ortholog_one2one ) Dog_ INTU ( ortholog_one2one ) GuineaPig_ INTU ( ortholog_one2one ) Macaque_ INTU ( ortholog_one2one ) Mouse_ Intu ( ortholog_one2one ) Pig_ INTU ( ortholog_one2one ) Rat_ NEWGENE_1309446 ( ortholog_one2one ) Rabbit_ INTU ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7Q3D (EM 3.35A ) |
| DBSNP | rs150681845 rs1360128571 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q059U7}. Cell surface {ECO:0000250|UniProtKB:Q2I0E5}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:26644512}. Note=Enriched at the apical surface in ciliated cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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