Gene Information
Gene NameINTS1
OrganismHomo sapiens (Human)
Gene Length2190
Protein NamesIntegrator complex subunit 1 (Int1)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000164880 )
Evolutionary StageEukaryota
AlphaFoldDBQ8N201
Gene CardINTS1
Uniprot IDQ8N201
PfamPF12432
In ASDno
Allosteric Predictionno (-0.388159025)
Ortholog in AnimalsAlpaca_ INTS1 ( ortholog_one2one )
Dog_ INTS1 ( ortholog_one2one )
GuineaPig_ INTS1 ( ortholog_one2one )
Macaque_ INTS1 ( ortholog_one2one )
Mouse_ Ints1 ( ortholog_one2one )
Pig_ INTS1 ( ortholog_one2one )
Rat_ Ints1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.034505(Mouse);0.067726(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7CUN  (EM  3.50A  7PKS  (EM  3.60A 
DBSNP rs200649090  rs3752714  rs1030646527  rs1162809128  rs1302980015 
Subcellular location [CC]Nucleus membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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