| Gene Information | |
|---|---|
| Gene Name | TM6SF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Transmembrane 6 superfamily member 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000136404 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9BZW5 |
| Gene Card | TM6SF1 |
| Uniprot ID | Q9BZW5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.581293568) |
| Ortholog in Animals | Alpaca_ TM6SF1 ( ortholog_one2one ) Dog_ TM6SF1 ( ortholog_one2one ) GuineaPig_ TM6SF1 ( ortholog_one2one ) Macaque_ TM6SF1 ( ortholog_one2one ) Mouse_ Tm6sf1 ( ortholog_one2one ) Pig_ TM6SF1 ( ortholog_one2one ) Rat_ Tm6sf1 ( ortholog_one2one ) Rabbit_ TM6SF1 ( ortholog_one2one ) |
| Ohnologs | TM6SF2 |
| Paralogs | TM6SF2 |
| Tissue | NA |
| Tissue Specificity | Enhanced expression in spleen, testis and peripheral blood leukocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1062232 rs1989 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000250|UniProtKB:P58749}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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