| Gene Information | |
|---|---|
| Gene Name | COX4I2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 171 |
| Protein Names | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (Cytochrome c oxidase subunit IV isoform 2) (COX IV-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000131055 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96KJ9 |
| Gene Card | COX4I2 |
| Uniprot ID | Q96KJ9 |
| Pfam | PF02936 |
| In ASD | no |
| Allosteric Prediction | no (-0.867236291) |
| Ortholog in Animals | Alpaca_ COX4I2 ( ortholog_one2many ) Dog_ COX4I2 ( ortholog_one2one ) GuineaPig_ COX4I2 ( ortholog_one2one ) Macaque_ COX4I2 ( ortholog_one2one ) Mouse_ Cox4i2 ( ortholog_one2one ) Pig_ COX4I2 ( ortholog_one2one ) Rat_ Cox4i2 ( ortholog_one2one ) Rabbit_ COX4I2 ( ortholog_one2one ) |
| Ohnologs | COX4I1 |
| Paralogs | COX4I1 |
| Tissue | placenta, adipose.tissue, heart, lung |
| Tissue Specificity | Highly expressed in lung. |
| Pharmacological Animal Models | 0.365229(Chimpanzee);0.335937(Mouse);NULL(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs119455950 rs11907253 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P00423}; Single-pass membrane protein {ECO:0000250|UniProtKB:P00423}. |
| Mouse PG classification | NA |
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