| Gene Information | |
|---|---|
| Gene Name | INO80J |
| Organism | Homo sapiens (Human) |
| Gene Length | 463 |
| Protein Names | RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y230 |
| Gene Card | RUVBL2 |
| Uniprot ID | Q9Y230 |
| Pfam | PF06068; PF17856 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in testis and thymus. {ECO:0000269|PubMed:10428817}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CQA (NMR - ) 2XSZ (X-ray 3.00A ) 3UK6 (X-ray 2.95A ) 5OAF (EM 4.06A ) 6FO1 (EM 3.57A ) 6H7X (X-ray 2.89A ) 6HTS (EM 4.80A ) 6IGM (EM 4.00A ) 6K0R (X-ray 2.50A ) 6QI8 (EM 3.75A ) 6QI9 (EM 4.63A ) 7AHO (EM 4.18A ) 7OLE (EM 3.41A ) 7P6X (EM 4.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Dynein axonemal particle {ECO:0000250|UniProtKB:Q9DE27}. Note=Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol. Although it is also present in the cytoplasm and associated with the cell membranes. |
| Mouse PG classification | NA |
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