| Gene Information | |
|---|---|
| Gene Name | CPSF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 471 |
| Protein Names | Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000149532 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N684 |
| Gene Card | CPSF7 |
| Uniprot ID | Q8N684 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.193159096) |
| Ortholog in Animals | Alpaca_ CPSF7 ( ortholog_one2one ) Dog_ CPSF7 ( ortholog_one2one ) GuineaPig_ CPSF7 ( ortholog_one2one ) Macaque_ CPSF7 ( ortholog_one2one ) Mouse_ Cpsf7 ( ortholog_one2one ) Pig_ CPSF7 ( ortholog_one2one ) Rat_ Cpsf7 ( ortholog_one2one ) Rabbit_ CPSF7 ( ortholog_one2one ) |
| Ohnologs | CPSF6 |
| Paralogs | CPSF6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3N9U (X-ray 1.92A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19864460, ECO:0000305|PubMed:20695905}. Cytoplasm {ECO:0000269|PubMed:19864460}. Note=Shuttles between the nucleus and the cytoplasm in a transcription- and XPO1/CRM1-independent manner, most probably in complex with the cleavage factor Im complex (CFIm) (PubMed:19864460). {ECO:0000269|PubMed:19864460}. |
| Mouse PG classification | NA |
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