| Gene Information | |
|---|---|
| Gene Name | INHBA |
| Organism | Homo sapiens (Human) |
| Gene Length | 426 |
| Protein Names | Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF) |
| Target Name | inhibin beta a chain |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122641 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P08476 |
| Gene Card | INHBA |
| Uniprot ID | P08476 |
| Pfam | PF00019; PF00688 |
| In ASD | no |
| Allosteric Prediction | no (-0.565969321) |
| Ortholog in Animals | Alpaca_ INHBA ( ortholog_one2one ) Dog_ INHBA ( ortholog_one2one ) Macaque_ INHBA ( ortholog_one2one ) Mouse_ Inhba ( ortholog_one2one ) Pig_ INHBA ( ortholog_one2one ) Rat_ Inhba ( ortholog_one2one ) Rabbit_ INHBA ( ortholog_one2one ) |
| Ohnologs | INHBE, INHBC, INHBB |
| Paralogs | BMP3, MSTN, INHBC, GDF15, BMP6, GDF6, TGFB3, BMP2, BMP10, TGFB1, INHA, GDF9, GDF11, BMP5, BMP7, INHBB, GDF5, GDF1, GDF2, BMP4, LEFTY1, LEFTY2, GDF3, INHBE, GDF7, GDF10, BMP15, TGFB2, BMP8A, BMP8B, NODAL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1NYS (X-ray 3.05A ) 1NYU (X-ray 3.10A ) 1S4Y (X-ray 2.30A ) 2ARP (X-ray 2.00A ) 2ARV (X-ray 2.00A ) 2B0U (X-ray 2.80A ) 2P6A (X-ray 3.40A ) 3B4V (X-ray 2.48A ) 4MID (X-ray 2.14A ) 5HLY (X-ray 2.30A ) 5HLZ (X-ray 2.85A ) 6Y6N (X-ray 2.03A ) 6Y6O (X-ray 2.04A ) 7OLY (X-ray 3.27A ) 7U5P (X-ray 3.14A ) |
| DBSNP | rs41294833 rs1361491625 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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