| Gene Information | |
|---|---|
| Gene Name | ING2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 280 |
| Protein Names | Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000168556 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H160 |
| Gene Card | ING2 |
| Uniprot ID | Q9H160 |
| Pfam | PF12998 |
| In ASD | no |
| Allosteric Prediction | no (-0.091051414) |
| Ortholog in Animals | Alpaca_ ING2 ( ortholog_one2one ) Dog_ ING2 ( ortholog_one2one ) GuineaPig_ ING2 ( ortholog_one2one ) Macaque_ ING2 ( ortholog_one2one ) Mouse_ Ing2 ( ortholog_one2one ) Pig_ ING2 ( ortholog_one2one ) Rat_ Ing2 ( ortholog_one2one ) Rabbit_ ING2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ING3, ING4, ING5, ING1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Higher expressed in colon-cancer tumor than in normal colon tissues. {ECO:0000269|PubMed:10072587}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001490(Rat);0.004762(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12859901}. Note=Predominantly nuclear. Localized to chromatin and nuclear matrix. Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm. |
| Mouse PG classification | NA |
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