| Gene Information | |
|---|---|
| Gene Name | IMPG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 797 |
| Protein Names | Interphotoreceptor matrix proteoglycan 1 (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000112706 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q17R60 |
| Gene Card | IMPG1 |
| Uniprot ID | Q17R60 |
| Pfam | PF01390 |
| In ASD | no |
| Allosteric Prediction | no (-1.446308372) |
| Ortholog in Animals | Alpaca_ IMPG1 ( ortholog_one2one ) Dog_ IMPG1 ( ortholog_one2one ) GuineaPig_ IMPG1 ( ortholog_one2one ) Macaque_ IMPG1 ( ortholog_one2one ) Mouse_ Impg1 ( ortholog_one2one ) Pig_ IMPG1 ( ortholog_one2one ) Rat_ Impg1 ( ortholog_one2one ) Rabbit_ IMPG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IMPG2 |
| Tissue | NA |
| Tissue Specificity | Expressed in the retina (at protein level) (PubMed:10601738, PubMed:29777959). In the retina, specifically expressed by cone and rod photoreceptor cells (PubMed:9813076). Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina (PubMed:9719680). {ECO:0000269|PubMed:10601738, ECO:0000269|PubMed:29777959, ECO:0000269|PubMed:9719680, ECO:0000269|PubMed:9813076}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs713993047 rs713993045 rs9443201 rs3734311 rs3734312 rs10943299 rs3734313 rs3778005 |
| Subcellular location [CC] | Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:29777959}. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix {ECO:0000269|PubMed:29777959, ECO:0000269|PubMed:9719680, ECO:0000269|PubMed:9813076}. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q8R1W8}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |