| Gene Information | |
|---|---|
| Gene Name | MAGED2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 606 |
| Protein Names | Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000102316 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9UNF1 |
| Gene Card | MAGED2 |
| Uniprot ID | Q9UNF1 |
| Pfam | PF01454 |
| In ASD | no |
| Allosteric Prediction | yes (0.302640576) |
| Ortholog in Animals | Alpaca_ MAGED2 ( ortholog_one2many ) Dog_ MAGED2 ( ortholog_one2one ) Macaque_ MAGED2 ( ortholog_one2one ) Mouse_ Maged2 ( ortholog_one2one ) Rat_ Maged2 ( ortholog_one2one ) Rabbit_ MAGED2 ( ortholog_one2one ) |
| Ohnologs | MAGEF1 |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. In the developing and adult kidney, expressed in the thick ascending limb of the loop of Henle and the distal convoluted tubules outside the loop. {ECO:0000269|PubMed:11856887, ECO:0000269|PubMed:27120771}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs12014977 rs1021000890 rs878854407 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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